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1 year ago
ECO 2024 — Dr Donna H Ryan (Pennington Biomedical Research Center, US) joins us to discuss the first sub-analysis of the landmark SELECT trial (NCT03574597, Novo Nordisk).In this study, investigators looked at long-term weight loss with semaglutide 2.4 mg compared to a placebo among 17,604 participants. In SELECT, at 208 weeks, semaglutide produced clinically significant weight loss compared to…
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7 months ago
ESC Congress 2025 - The SEMA-VR CardioLink-15 trial revealed that semaglutide may enhance endogenous progenitor cell-mediated vasculogenic repair processes.Dr Subodh Verma (University of Toronto, Toronto, CA) joins us to discuss the findings from the SEMA-VR CardioLink-15 trial. The study compared usual care with semaglutide, GLP-1RA for six months in 46 patients with either type 2 diabetes…
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1 year ago
EASD 24 - We are joined by Dr Helen Coulhoun (University of Edinburgh, UK) to discuss the key findings of a prespecified analysis of the SELECT trial, which investigated the effectiveness of semaglutide in reducing major cardiac events in the presence of impaired kidney function in patients with overweight and obesity.Findings showed that participants in the study with reduced eGFR and/or…
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5 months ago
AHA Scientific Sessions 2025 - Dr Milton Packer (Baylor University Medical Center, US) joins us to discuss his novel unifying hypothesis that heart failure with preserved ejection fraction arises primarily from visceral adipose tissue dysfunction and altered adipokine signaling, rather than as a heterogeneous disorder driven by multiple comorbidities.Interview Questions:Can you explain the core…
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1 year ago
As part of e-SPACE Cardio-Renal-Metabolic 2024, Dr Scott Isaacs, Prof Peter Rossing, Dr Muthiah Vaduganathan, Prof Stefan Anker and Dr Javed Butler discuss weight management for CRM disease.
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1 year ago
As part of e-SPACE Cardio-Renal-Metabolic 2024, Prof John Cleland, Prof Gerasimos Filippatos, Prof Ewa Jankowska, Prof David Wheeler, Dr Kieran Docherty discuss anaemia and iron deficiency.
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1 year ago
ECO 2024 — Prof Sven Francque (University of Antwerp, BE) joins us to talk about the new EASL-EASD-EASO Practice Guidelines for MAFLD.In this interview, Prof Francque highlights some of the unmet needs in people with MAFLD (formerly known as NAFLD). He then summarises the key highlights of the latest guidelines, including guidance on treatment options. He also discusses some of the challenges…
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1 year ago
ACC 2025 - Individual-level data collected across 126 worldwide cohorts show controlling modifiable cardiovascular risk factors can potentially benefit life-years for freedom from CVD and death from any cause.Prof Christina Magnussen (University Heart and Vascular Centre Hamburg, Hamberg, DE) joins us onsite at ACC to discuss modifiable cardiovascular risk factors collected by the Global…
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1 year ago
AHA Conference 2024 - In this highlights video from AHA 2024, Dr Michelle Kittleson (Cedars-Sinai California Heart Center, US) offers a concise and insightful summary of the most influential late-breaking trials presented at the conference. Dr Kittleson discusses the pivotal studies poised to impact clinical practice and enhance patient outcomes in heart failure care.Trials covered in detail…
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5 months ago
AHA Scientific Sessions 2025 - Dr Emily Lau (Brigham and Women's Hospital, US) joins us to discuss what cardiologists need to know about the intersection of pregnancy and cardiovascular-kidney-metabolic health, from pre-conception counseling through long-term postpartum care.Interview Questions:Why is it important for cardiologists to understand the relationship between pregnancy and…
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